{"id":1075,"date":"2021-03-02T08:46:58","date_gmt":"2021-03-02T08:46:58","guid":{"rendered":"http:\/\/www.cscr.in\/nahd\/?page_id=1075"},"modified":"2021-05-18T08:23:46","modified_gmt":"2021-05-18T08:23:46","slug":"home-new","status":"publish","type":"page","link":"https:\/\/www.cscr.res.in\/nahd\/","title":{"rendered":"Home"},"content":{"rendered":"<div id=\"pl-1075\"  class=\"panel-layout\" ><div id=\"pg-1075-0\"  class=\"panel-grid panel-has-style\" ><div class=\"abt-sec1 panel-row-style panel-row-style-for-1075-0\" ><div id=\"pgc-1075-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3 class=\"title-abt1\">About The Program<\/h3>\n<p class=\"sp-para\" style=\"text-align: justify; margin: 0;\"><strong>Novel Approaches to Haematological Diseases (NAHD)<\/strong> is part of the program entitled Accelerating the application of Stem cell technology in Human Disease (ASHD), an Indo-Japan collaborative project, supported by the Department of Biotechnology, Ministry of Science and Technology, Government of India. This program aims to exploit cutting-edge biotechnology applied to stem cell science and human genetics to range of clinical applications including gene therapy for haematological diseases to address several unmet needs in the country. The major components of the NAHD program are (i) Gene Therapy for the common hereditary haematological disorders such as thalassemia major, sickle cell disease and haemophilia (ii) Haplobanking to create a cell bank of HLA haplo-identical induced pluripotent stem cells for regenerative medicine and (iii) Establishing a model for the control and prevention of thalassemia major and sickle cell disease in the community.<\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-1075-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"abt-right1 panel-widget-style panel-widget-style-for-1075-0-1-0\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\"><h3 class=\"widget-title\">News &amp;  Recent Developments <\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class='container-fluid rt-tpg-container rt-tpg-container-1088 ' data-sc-id='1088' id='rt-tpg-container-1560657084'><div class='rt-row rt-content-loader layout1'><style type='text\/css' media='all'>#rt-tpg-container-1560657084 .rt-detail i,\n                        #rt-tpg-container-1560657084 .rt-detail .post-meta-user a,\n                        #rt-tpg-container-1560657084 .rt-detail .post-meta-category a{color:#0367bf;}body .rt-tpg-container .rt-tpg-isotope-buttons .selected{background-color:#0367bf;}<\/style><div class=\"rt-col-lg-12 rt-col-md-12 rt-col-sm-6 rt-col-xs-12 rt-equal-height\" data-id=\"2652\"><div class=\"rt-holder\"><div class=\"rt-detail\"><h2 class=\"entry-title\"><a href=\"https:\/\/www.cscr.res.in\/nahd\/lentiviral-gene-therapy-approach-for-haemoglobinopathies\/\">Lentiviral Gene Therapy Approach for Haemoglobinopathies<\/a><\/h2><\/div><\/div><\/div><div class=\"rt-col-lg-12 rt-col-md-12 rt-col-sm-6 rt-col-xs-12 rt-equal-height\" data-id=\"1411\"><div class=\"rt-holder\"><div class=\"rt-detail\"><h2 class=\"entry-title\"><a href=\"https:\/\/www.cscr.res.in\/nahd\/aav-antibody-assay-2\/\">AAV Antibody Assay<\/a><\/h2><\/div><\/div><\/div><div class=\"rt-col-lg-12 rt-col-md-12 rt-col-sm-6 rt-col-xs-12 rt-equal-height\" data-id=\"1403\"><div class=\"rt-holder\"><div class=\"rt-detail\"><h2 class=\"entry-title\"><a href=\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/\">iPSC Technology<\/a><\/h2><\/div><\/div><\/div><\/div><\/div>\n<p class=\"viwall1\"><a href=\"http:\/\/www.cscr.res.in\/nahd\/news-recent-developments\/\">View All<\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-1075-1\"  class=\"panel-grid panel-has-style\" ><div class=\"components-sec1 siteorigin-panels-stretch panel-row-style panel-row-style-for-1075-1\" data-stretch-type=\"full\" ><div id=\"pgc-1075-1-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-1-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"2\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>Major Components of the Program<\/h3>\n<\/div>\n<\/div><\/div><div id=\"panel-1075-1-0-1\" class=\"so-panel widget widget_siteorigin-panels-builder panel-last-child\" data-index=\"3\" ><div id=\"pl-w60a37992b252b\"  class=\"panel-layout\" ><div id=\"pg-w60a37992b252b-0\"  class=\"panel-grid panel-has-style\" ><div class=\"rows-css12 panel-row-style panel-row-style-for-w60a37992b252b-0\" ><div id=\"pgc-w60a37992b252b-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-w60a37992b252b-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><img loading=\"lazy\" class=\"size-full wp-image-1115 aligncenter\" src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/gene-icon1.png\" alt=\"Gene Therapy\" width=\"\" height=\"\" \/><\/p>\n<h4 style=\"text-align: center;\">Gene Therapy<\/h4>\n<p class=\"dec-css1\" style=\"text-align: center;\">The NAHD program envisages to develop novel methods for gene therapy of hereditary blood disorders such as haemophilia, thalassemia and sickle cell disease.<\/p>\n<p class=\"rdmcss1\"><a href=\"http:\/\/www.cscr.res.in\/nahd\/gene-therapy-program\/\"><u>Read More<\/u><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-w60a37992b252b-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-w60a37992b252b-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><img loading=\"lazy\" class=\"size-full wp-image-1115 aligncenter\" src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/icon2-sp.png\" alt=\"Applications of Induced Pluripotent Stem Cell (iPSC) Technology: Haplobanking\" width=\"\" height=\"\" \/><\/p>\n<h4 style=\"text-align: center;\">Applications of Induced Pluripotent Stem Cell (iPSC) Technology: Haplobanking<\/h4>\n<p class=\"dec-css1\" style=\"text-align: center;\">The NAHD program intends to create a bank of cells from individuals with homozygous HLA haplotype called the Haplobank with an aim to develop the field. <\/p>\n<p class=\"rdmcss1\"><a href=\"http:\/\/www.cscr.res.in\/nahd\/haplobanking\/\"><u>Read More<\/u><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-w60a37992b252b-0-2\"  class=\"panel-grid-cell\" ><div id=\"panel-w60a37992b252b-0-2-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"2\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><img loading=\"lazy\" class=\"aligncenter size-full wp-image-1441\" src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/affected-child2-img.jpg\" alt=\"Control of Thalassemia &amp; Sickle Cell Disease program for Odisha\" width=\"\" height=\"\" \/><\/p>\n<h4 style=\"text-align: center;\">Control of Thalassemia &amp; Sickle Cell Disease program for Odisha<\/h4>\n<p class=\"dec-css1\" style=\"text-align: center;\">Under the NAHD program, CSCR and   CMC,   Vellore   have   taken initiative   to  develop a model for community outreach program for the control of major haemoglobin disorders.<\/p>\n<p class=\"rdmcss1\"><a href=\"http:\/\/www.cscr.res.in\/nahd\/control-of-thalassemia-sickle-cell-disease-program-for-odisha\/\"><u>Read More<\/u><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-1075-2\"  class=\"panel-grid panel-has-style\" ><div class=\"last-sec1 siteorigin-panels-stretch panel-row-style panel-row-style-for-1075-2\" data-stretch-type=\"full\" ><div id=\"pgc-1075-2-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-2-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"4\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\"><h3 class=\"widget-title\">Collaborators<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul class=\"liststycss-s\">\n<li><a href=\"https:\/\/winshipcancer.emory.edu\/bios\/faculty\/spencer-h-trent.html\" target=\"_blank\" rel=\"noopener\"><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/02\/1a.jpg\" \/><\/a><\/li>\n<li><a href=\"https:\/\/srivastava.cellular.pediatrics.med.ufl.edu\/profile\/srivastava-arun\/\" target=\"_blank\" rel=\"noopener\"><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/01\/2a.jpg\" \/><\/a><\/li>\n<li><a href=\"http:\/\/histogenetics.com\/about\" target=\"_blank\" rel=\"noopener\"><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/01\/3a.jpg\" \/><\/a><\/li>\n<li class=\"h-list-col\"><a href=\"http:\/\/datri.org\/\" target=\"_blank\" rel=\"noopener\"><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/01\/4a.jpg\" \/><\/a><\/li>\n<li><a href=\"https:\/\/www.cira.kyoto-u.ac.jp\/e\/\" target=\"_blank\" rel=\"noopener\"><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/01\/5a.jpg\" \/><\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-1075-2-1\"  class=\"panel-grid-cell\" ><div class=\"img-algsingle1 panel-cell-style panel-cell-style-for-1075-2-1\" ><div id=\"panel-1075-2-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"5\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\"><h3 class=\"widget-title\">Funding &amp; support<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><img src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/02\/dep-bio.jpg\" alt=\"\"  class=\"size-full wp-image-448\" \/><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-1075-3\"  class=\"panel-grid panel-has-style\" ><div class=\"panel-row-style panel-row-style-for-1075-3\" ><div id=\"pgc-1075-3-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-3-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"6\" ><div class=\"cmnycss1 panel-widget-style panel-widget-style-for-1075-3-0-0\" ><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"home-contact\">\n<h3 class=\"title-abt1-1\">Reach Us<\/h3>\n<\/div>\n<div class=\"sp-col-wh\">\n<ul class=\"reachus\">\n<li class=\"company\">Centre for Stem Cell Research (a unit of inStem, Bengaluru),<br \/>\nChristian Medical College Campus, Bagayam, Vellore - 632002,<br \/>\nTamilNadu, India.<\/li>\n<li class=\"mobile\"><a href=\"tel:+914163075101\">+91 416 3075101,<\/a> <a href=\"tel:+914163075107\">3075107,<\/a> <a href=\"tel:+914163075120\">3075120<\/a><\/li>\n<li class=\"fax\">+91 416 307 5103<\/li>\n<li class=\"email\"><a href=\"mailto:cscr@cmcvellore.ac.in\">cscr@cmcvellore.ac.in<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pgc-1075-3-1\"  class=\"panel-grid-cell\" ><div id=\"panel-1075-3-1-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"7\" ><div class=\"home-center-abt-img panel-widget-style panel-widget-style-for-1075-3-1-0\" ><div class=\"so-widget-sow-image so-widget-sow-image-default-6b88c04c1f9b\">\n\n<div class=\"sow-image-container\">\n\t<img src=\"https:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/CSCR-building.jpg\" width=\"382\" height=\"202\" srcset=\"https:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/CSCR-building.jpg 382w, https:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/CSCR-building-300x159.jpg 300w\" sizes=\"(max-width: 382px) 100vw, 382px\" title=\"CSCR building\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n<\/div>\n\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>IPSC Technology An efficient method for the generation of iPSCs from erythroid progenitors has been established iPSC lines have been generated from 6 normal donors which are available for researchers. Methods for efficient gene editing of iPSCs using CRISPR-Cas9 have been established for disease modelling and mutation correction. Robust methods have been standardized for the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v16.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>Home - CSCR NAHD<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.cscr.res.in\/nahd\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"Home - CSCR NAHD\" \/>\r\n<meta property=\"og:description\" content=\"IPSC Technology An efficient method for the generation of iPSCs from erythroid progenitors has been established iPSC lines have been generated from 6 normal donors which are available for researchers. Methods for efficient gene editing of iPSCs using CRISPR-Cas9 have been established for disease modelling and mutation correction. Robust methods have been standardized for the [&hellip;]\" \/>\r\n<meta property=\"og:url\" content=\"https:\/\/www.cscr.res.in\/nahd\/\" \/>\r\n<meta property=\"og:site_name\" content=\"CSCR NAHD\" \/>\r\n<meta property=\"article:modified_time\" content=\"2021-05-18T08:23:46+00:00\" \/>\r\n<meta property=\"og:image\" content=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/gene-icon1.png\" \/>\r\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\r\n<meta name=\"twitter:label1\" content=\"Est. reading time\">\n\t<meta name=\"twitter:data1\" content=\"1 minute\">\r\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#website\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"name\":\"CSCR NAHD\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":\"https:\/\/www.cscr.res.in\/nahd\/?s={search_term_string}\",\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#primaryimage\",\"inLanguage\":\"en-US\",\"url\":\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/gene-icon1.png\",\"contentUrl\":\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/gene-icon1.png\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#webpage\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"name\":\"Home - CSCR NAHD\",\"isPartOf\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#primaryimage\"},\"datePublished\":\"2021-03-02T08:46:58+00:00\",\"dateModified\":\"2021-05-18T08:23:46+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.cscr.res.in\/nahd\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"item\":{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"position\":2,\"item\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#webpage\"}}]}]}<\/script>\r\n<!-- \/ Yoast SEO plugin. -->","_links":{"self":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/pages\/1075"}],"collection":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/comments?post=1075"}],"version-history":[{"count":132,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/pages\/1075\/revisions"}],"predecessor-version":[{"id":3100,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/pages\/1075\/revisions\/3100"}],"wp:attachment":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/media?parent=1075"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}