{"id":1403,"date":"2021-03-04T02:58:33","date_gmt":"2021-03-04T02:58:33","guid":{"rendered":"http:\/\/www.cscr.in\/nahd\/?p=1403"},"modified":"2021-05-10T10:39:35","modified_gmt":"2021-05-10T10:39:35","slug":"ipsc-technology","status":"publish","type":"post","link":"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/","title":{"rendered":"iPSC Technology"},"content":{"rendered":"<div id=\"pl-1403\"  class=\"panel-layout\" ><div id=\"pg-1403-0\"  class=\"panel-grid panel-has-style\" ><div class=\"panel-row-style panel-row-style-for-1403-0\" ><div id=\"pgc-1403-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1403-0-0-0\" class=\"widget_text so-panel widget widget_custom_html panel-first-child\" data-index=\"0\" ><div class=\"textwidget custom-html-widget\"><div class=\"sp-title-cscr-post title-mbottom text-left\">\n<h3>IPSC Technology<\/h3>\n<\/div>\n<ul class=\"list-post-sp\">\t\n<li>An efficient method for the generation of iPSCs from erythroid progenitors has been established<\/li>\n<li>iPSC lines have been generated from 6 normal donors which are available for researchers.<\/li>\n<li>Methods for efficient gene editing of iPSCs using CRISPR-Cas9 have been established for disease modelling and mutation correction.<\/li>\n<li>Robust methods have been standardized for the differentiation of iPSCs to haematopoietic progenitors and erythroid cells.<\/li>\n<li>An iPSC line that expresses Cas9 from AAVS1 safe harbour site has been generated for efficient gene editing of the target genes<\/li>\n<li>Currently, experiments to study the disease mechanisms and drug screening for haematological diseases are being carried out.<\/li>\n<\/ul><\/div><\/div><div id=\"panel-1403-0-0-1\" class=\"widget_text so-panel widget widget_custom_html\" data-index=\"1\" ><div class=\"textwidget custom-html-widget\"><div class=\"sp-co-sub\">\n<p>\n<span class=\"color-red\">Principal Investigator:<\/span><br>\n\t<a class=\"ref-color-anchor-black\" href=\"http:\/\/www.cscr.res.in\/dr-shaji-r-velayudhan\/\" target=\"_blank\" rel=\"noopener\"><span class=\"color-bold-1\">Dr. Shaji R.V.,<\/span> <span class=\"inves-dept\">Department of Haematology, CMC and CSCR, Vellore<\/span><\/a>\n<\/p>  \t\n<\/div><\/div><\/div><div id=\"panel-1403-0-0-2\" class=\"so-panel widget widget_media_image panel-last-child\" data-index=\"2\" ><img class=\"image \" src=\"http:\/\/www.cscr.res.in\/nahd\/jb-content\/uploads\/2021\/03\/ipsc-post.jpg\" alt=\"ipsc-post\" width=\"410\" height=\"230\" \/><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>IPSC Technology An efficient method for the generation of iPSCs from erythroid progenitors has been established iPSC lines have been generated from 6 normal donors which are available for researchers. Methods for efficient gene editing of iPSCs using CRISPR-Cas9 have been established for disease modelling and mutation correction. Robust methods have been standardized for the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[25],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v16.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>iPSC Technology - CSCR NAHD<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"iPSC Technology - CSCR NAHD\" \/>\r\n<meta property=\"og:description\" content=\"IPSC Technology An efficient method for the generation of iPSCs from erythroid progenitors has been established iPSC lines have been generated from 6 normal donors which are available for researchers. Methods for efficient gene editing of iPSCs using CRISPR-Cas9 have been established for disease modelling and mutation correction. Robust methods have been standardized for the [&hellip;]\" \/>\r\n<meta property=\"og:url\" content=\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/\" \/>\r\n<meta property=\"og:site_name\" content=\"CSCR NAHD\" \/>\r\n<meta property=\"article:published_time\" content=\"2021-03-04T02:58:33+00:00\" \/>\r\n<meta property=\"article:modified_time\" content=\"2021-05-10T10:39:35+00:00\" \/>\r\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\r\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#website\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"name\":\"CSCR NAHD\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":\"https:\/\/www.cscr.res.in\/nahd\/?s={search_term_string}\",\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/#webpage\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/\",\"name\":\"iPSC Technology - CSCR NAHD\",\"isPartOf\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#website\"},\"datePublished\":\"2021-03-04T02:58:33+00:00\",\"dateModified\":\"2021-05-10T10:39:35+00:00\",\"author\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#\/schema\/person\/901630f2506631b151a248df716d1cd0\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"item\":{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"url\":\"https:\/\/www.cscr.res.in\/nahd\/\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"position\":2,\"item\":{\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/ipsc-technology\/#webpage\"}}]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#\/schema\/person\/901630f2506631b151a248df716d1cd0\",\"name\":\"cscr-nahd\",\"image\":{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.cscr.res.in\/nahd\/#personlogo\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/2851170074b8dc7b944d37ba6e65f5de?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/2851170074b8dc7b944d37ba6e65f5de?s=96&d=mm&r=g\",\"caption\":\"cscr-nahd\"},\"sameAs\":[\"http:\/\/www.cscr.res.in\/nahd\"],\"url\":\"https:\/\/www.cscr.res.in\/nahd\/author\/nahd_userlogin\/\"}]}<\/script>\r\n<!-- \/ Yoast SEO plugin. -->","_links":{"self":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/posts\/1403"}],"collection":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/comments?post=1403"}],"version-history":[{"count":23,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/posts\/1403\/revisions"}],"predecessor-version":[{"id":2737,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/posts\/1403\/revisions\/2737"}],"wp:attachment":[{"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/media?parent=1403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/categories?post=1403"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cscr.res.in\/nahd\/wp-json\/wp\/v2\/tags?post=1403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}