10th Annual Cell and Gene Therapy Symposium

Centre for Stem Cell Research (a unit of inStem, Bengaluru), Christian Medical College Campus, Vellore

Scientific Programme 2024

9TH ANNUAL SYMPOSIUM ON CELL AND GENE THERAPY

1st  to 3rd  August, 2024

PROGRAMME SCHEDULE

DAY-1: Thursday, 1st  August, 2024

1:00 to 1:05 PM

1:05 to 1:20 PM

1:20 to 1:25 PM

1:25 to 1:30 PM

 ·         Prayer by Chaplain

·         Welcome remarks: Director, CMC / Director, InStem / Principal, CMC

·         Remarks by  Secretary, Department of Biotechnology, Ministry of Science and Technology, Govt. of India

·         Closing remarks: Head, CSCR
Session-1:  Orthobiologics In Cartilage Repair

Chair: Samuel Chittaranjan
India Time Title Speaker Name
1.30 to 2:00 PM Cell-Based Therapeutics for Arthritic Disease Frank Barry

University of Galway, Ireland
2:00 to 2:30 PM PRP for OA Knee: Bench to bedside Sandeep Patel

The Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
2:30 to 3:00 PM The Role of Extracellular Vesicles and Orthobiologics Secretome in Joint Preservation Elizabeth Vinod

Centre for Stem Cell Research (A unit of inStem, Bengaluru) and CMC, Vellore, India
3:00 to 3:30 PM Poster presentation and Industry Exhibition
Session-2: MANUFACTURING AND REGULATORY ASPECTS IN CELL AND GENE THERAPY

Chair: Cartikeya Reddy
India Time Title Speaker Name
3:30 to 4:00 PM Challenges and Promise of CAR-based therapies in India Akhil Kumar

Aurigene Oncology Limited, Bangalore, India

and

Priyadarshini Chatterjee

Aurigene Oncology Limited, Bangalore, India
4:00 to 4:30 PM From Innovation to Translation to Patients: The Future of Genetically Engineered T-Cells for Human Therapeutics Bruce L. Levine

The University of Pennsylvania,

Philadelphia, US
4:30 to 5:00 PM Mesenchymal stromal cells for clinical applications: CMC Challenges and Paths Forward Sowmya Viswanathan

Schroeder Arthritis Institute, University Health Network and the University of Toronto, Ontario, Canada
5:00 to 5:15 PM Break
Session-3: TECHNOLOGY ADVANCES

Chair: Soniya Nityanand
India Time Title Speaker Name
5:15 to 5:45 PM Development of targeted viral platform for selective gene transfer to human HSCs in vivo Dmitry M. Shayakhmetov

Emory University School of Medicine

Atlanta, USA
5:45 to 6:15 PM Genetic and Transcriptional Engineering of Primary Human Blood Cells Rasmus O. Bak

Aarhus University, Department of Biomedicine,

Aarhus, Denmark
6:15 to 6:45 PM Innovative Non-Genotoxic Cell and Gene Therapies for Fanconi Anemia Agnieszka Czechowicz

Stanford University School of Medicine, Dept of Pediatrics Div. of Stem Cell Transplantation and Regenerative Medicine, Stanford, US
KEYNOTE ADDRESS

Chair: Alok Srivastava
India Time Title Speaker Name
6:45 to 7:45 PM The Concept of Innovation and Orchestration: Translating Engineered Cellular Therapies from Bench to Bedside Khalid Shah

Center for Stem Cell and Translational Immunotherapy, Brigham and Women’s Hospital and Harvard Stem Cell Institute, Cambridge, USA
End of Day-1

 

DAY-2: Friday,  2nd  August, 2024

Session-4: INDUSTRY UPDATES

 Chair: Praveen Kumar Vemula
India Time Title Speaker Name
12:00  to 12:20 PM Non-Viral Chimeric Antigen Receptor (CAR) T Cells going Viral: Process Studies from Stanford Center for Cancer Cell Vimal Keerthi

Stanford University School of Medicine,

California, US
12: 20  to 12:40 PM Writing the Future of Biologics with an Integrated Offering of Immunization, Libraries, and Machine Learning Jay Yang

Twist Bioscience, San Francisco,

California, US
12:40  to 1:00 PM Transforming Viral Vector Production: Enhancing Efficiency and Scale-Up with OmniBRx’s Dynamic Bed Reactor Technology  Ravindra Patel

OmniBRx Biotechnologies Pvt Ltd.

Ahmedabad, Gujarat, India
1:00  to 2:00 PM Lunch Break
                        Session-5: APPLICATION OF IPSC TECHHNOLOGY

Chair: Maneesha S. Inamdar
India Time Title Speaker Name
2:00 to 2:30 PM Challenges for the development of pluripotent stem cell based therapies and the role of international standards. Glyn Stacey

International Stem Cell Banking Initiative, Barley, UK
2:30 to 3:00 PM Developing iPSC-derived RPE cell replacement therapy for the treatment of AMD Rajarshi Pal

Eyestem Research, Centre for Cellular and Molecular Platforms (C-CAMP), Bangalore, India
3:00 to 3:30 PM iPSC based disease modelling R V Shaji
Centre for Stem Cell Research (a unit of inStem, Bengaluru) and CMC, Vellore, India
3:30 to 3:45 PM Break
 Session-6: GENE THERAPY

Chair: Ullas Kolthur-Seetharam
India Time Title Speaker Name
3:45 to 4.15 PM New insights into the use of gamma delta T cells to treat childhood cancers H. Trent Spencer

Emory University School of Medicine,

Atlanta, USA
4:15 to 4:45 PM Development of genome-modified generation ZZ (GenZZ) single-stranded AAV vectors with improved transgene expression Arun Srivastava

University of Florida, Florida, USA
4:45 to 5:15 PM Preclinical development of gene therapy for Diamond-Blackfan anemia Senthil Bhoopalan                

St. Jude Children’s Research Hospital,

Memphis, USA
5:15 to 6:00 PM Poster presentation and Industry Exhibition
Session-7: Challenges And Opportunities In Gene Therapy

Chair: RV Shaji
India Time Title Speaker Name
6:00 to 6:30 PM Development of pathophysiologicallyrelevant models of β-hemoglobinopahtues for therapeutic studies Sivaprakash Ramalingam

CSIR–Institute Of Genomics And Integrative Biology (CSIR–IGIB), New Delhi, India
6:30 to 7:00 PM CAR T-cell induced T-cell malignancies

Nirali Shah

Center for Cancer Research, National Cancer Institute, Maryland, US
7:00 to 7:30 PM Genome Editing of HSCs to Develop Stem Cell Based Therapies Matthew Porteus

Stanford School of Medicine,

California, USA
KEY NOTE ADDRESS

Chair: Sanjay Singh
India Time Title Speaker Name
7:30 to 8:30 PM Gene therapy for Haemophilia in India – The beginning of a new era Alok Srivastava

Christian Medical College

and Centre for Stem Cell Research Vellore, India
End of Day-2

 

 

 

DAY-3: Saturday,  3rd  August, 2024

Session-8: INDUSTRY UPDATES
India Time Title Speaker Name
12:20  to 12:40 PM Autologous CAR-T Cell Therapy Manufacturing Solution Pankaj Salvi

Cytiva, Marlborough, US
12:40  to 01:00 PM Thermo Fisher Scientific: Cell & Gene Therapy capabilities overview Uchenna Waturuocha

Thermo Fisher Scientific,

Mumbai, India
01:00 to 02:00 PM Lunch Break
Session-9: NON-VIRAL VECTOR BASED GENE THERAPY

Chair: N. Madhusudhana Rao
India Time Title Speaker Name
2:00 to 2:30 PM Enhancing Natural killer cells proliferation and cytotoxicity using Imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA Chantal Pichon

INSERM and University of Orléans, Orléans, France: Institut Universitaire de France, Paris

2:30 to 3:00 PM

 MSC Extracellular Vesicles: Navigating Regenerative Medicine’s Therapeutic Landscape Sujata Mohanty

All India Institute of Medical Sciences

New Delhi, India
3:00 to 3:30 PM Sugar-alcohol modified poly(beta-amino) ester nanoparticles for gene delivery to the brain Munia Ganguli

Institute of Genomics and Integrative Biology

(CSIR-IGIB), New Delhi, India
3:30 to 3:45 PM Break
3:45 to 4:30 PM Poster presentation and Industry Exhibition
Session-10: GENE EDITING

Chair: Sanjeev Galande
India Time Title Speaker Name
4:30 to 5:00 PM Genome editing strategies for treating sickle cell disease Thiyagaraj Mayuranathan

Centre for Stem Cell Research (A unit of inStem, Bengaluru), Vellore, India
5:00 to 5:30 PM Epitope Editing for an Immunotherapy “Stealth” Hematopoiesis Pietro Genovese

Harvard Medical School,

Boston, USA
5:30 to 6:00 PM Next-generation gene editing of human hematopoietic stem cells: from research to clinical translation Samuele Ferrari

San Raffaele Telethon Institute for Gene Therapy

(SR-Tiget), Milan, Italy
Session-11: IMMUNE CELL THERAPY

Chair: Amit Awasthi
 

India Time

 Title Speaker Name
6:00 to 6:30 PM CART Therapy in Pediatric Acute Lymphoblastic Leukemia Sunil Bhat

Mazumdar Shaw Medical Centre, Narayana Health City, Bangalore, India
6:30 to 7:00 PM Development of CAR-T cell products with non-viral vector system Yoshiyuki Takahashi

Nagoya University Graduate School of Medicine,

Nagoya, Japan
7:00 to 7:30 PM Genetic manipulation of NK cells for enhanced immunotherapy  Rizwan Romee

Harvard Medical School, Dana Farber Cancer Institute, Boston, USA
CONCLUDING REMARK
End of Day-3