Journals
  • George A, Ravi NS, Prasad K, Panigrahi L, Koikkara S, Rajendiran V, Devaraju N, Paul J, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, Mohankumar KM. Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2, Front Genome Ed. 2022 Dec 20;4:1085111. doi: 10.3389/fgeed.2022.1085111
  • Venkatesan V, Christopher A, Karuppusamy K, Babu P, Azhagiri M and Thangavel S. CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications. JoVE. August 9, 2022 doi: 10.3791/64064
  • Eekhoff EMW, de Ruiter RD, Smilde BJ, Schoenmaker T, de Vries TJ, Netelenbos C, Hsiao EC, Scott C, Haga N, Grunwald Z, De Cunto CL, di Rocco M, Delai PLR, Diecidue RJ, Madhuri V, Cho TJ, Morhart R, Friedman CS, Zasloff M, Pals G, Shim JH, Gao G, Kaplan F, Pignolo RJ, Micha D. Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles. Hum Gene Ther. 2022 Aug;33(15-16):782-788.
  • Rapaka H, Manturthi S, Arjunan P, Venkatesan V, Thangavel S, Marepally S, Patri S V. Influence of Hydrophobicity in the Hydrophilic Region of Cationic Lipids on Enhancing Nucleic Acid Delivery and Gene Editing. ACS Appl bio Mater (2022) 5:1489–1500
  • Chilbule SK, Rajagopal K, Walter N, Dutt V, Madhuri V. Role of WNT Agonists, BMP and VEGF Antagonists in Rescuing Osteoarthritic Knee Cartilage in a Rat Model. Indian J Orthop. 2022;56(1):24–33.
  • Franklyn J, Ramesh S, Madhuri V, Patel B, Dhivya A, Nair PD, et al. Abdominal Wall Reconstruction with Tissue-Engineered Mesh Using Muscle-Derived Stem Cells in an Animal Model. Regenerative Engineering and Translational Medicine (2022).
  • James D, Subramanian L, Selina A, Palocaren T, Madhuri V. Novel TRPV4 Pathogenic Variant in Severe Metatropic Skeletal Dysplasia: A Case Report. Malays Orthop J. 2022 Jul;16(2):145-149.
  • Jehangir S, Ramesh S, Thomas M, Madhuri V. Wharton’s Jelly Mesenchymal Stem Cells on a Novel Aloe Vera-Polycaprolactone (A-PCL) Composite Scaffold in Burns. Regenerative Engineering and Translational Medicine (2022) (1).
  • Reiss UM, Mahlangu J, Ohmori T, Ozelo MC, Srivastava A, Zhang L. Haemophilia gene therapy-Update on new country initiatives. Haemophilia. 2022 May;28 Suppl 4:61-67. doi: 10.1111/hae.14512. PMID: 35521726.
  • Cuende N, Ciccocioppo R, Forte M, Galipeau J, Ikonomou L, Levine BL, Srivastava A, Zettler PJ. Patient access to and ethical considerations of the application of the European Union hospital exemption rule for advanced therapy medicinal products. Cytotherapy. 2022 Jul;24(7):686-690. doi: 10.1016/j.jcyt.2022.03.007. Epub 2022 May 8. PMID: 35545453.
  • Christopher AC, Venkatesan V, Karuppusamy KV, Srinivasan S, Babu P, Azhagiri MKK, Chambayil K, Bagchi A, Rajendiran V, Ravi NS, Kumar S, Marepally SK, Mohankumar KM, Srivastava A, Velayudhan SR, Thangavel S. Preferential Expansion of Human CD34+CD133+CD90+ Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy. Hum Gene Ther. 2022 Feb;33(3-4):188-201. doi: 10.1089/hum.2021.089. Epub 2022 Jan 7. PMID: 34486377.
  • Singh G, Manian KV, Premkumar C, Srivastava A, Daniel D, Velayudhan SR. Derivation of Clinical-Grade Induced Pluripotent Stem Cell Lines from Erythroid Progenitor Cells in Xenofree Conditions. Methods Mol Biol. 2022; 2454:775-789. doi: 10.1007/7651_2021_349. PMID: 33950379.
  • Thamodaran V, Rani S, Velayudhan SR. Gene Editing in Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible CRISPR-Cas9 System. Methods Mol Biol. 2022; 2454:755-773. doi: 10.1007/7651_2021_348. PMID: 33830454.
  • Prasad K, Devaraju N, George A, Ravi NS, Mahalingam G, … Mohankumar KM* et al. Precise modelling and correction of a spectrum of β-thalassemic mutations in human erythroid cells by base editors [Internet]. bioRxiv; 2022 [cited 2022 Jun 13]. p. 2022.06.01.494256.(biorxiv preprint)
  • Tejram Sahu*, Srujan Marepally*, Rajeev Tyagi* Editorial: Nanomedicine in infectious diseases: Drug delivery and vaccines Frontiers in Pharmacology, Front Pharmacol. 2022 Aug 17;13:928572.
  • Rapaka H, Manturthi S, Gosangi M, Lohchania B, Marepally S*, Patri SV*. Effect of Methylation of the Hydrophilic Domain of Tocopheryl Ammonium-Based Lipids on their Nucleic Acid Delivery Properties. ACS Omega. 2022 7(18):15396-15403. doi:10.1021/acsomega. 1c06889.
  • Hari Krishnareddy Rachamalla, Chandrashekhar Voshavar, Porkizhi arjunan, Gokulnath Mahalingam, Rashmi Praksash Chowath, Rajkumar Banerjee*, Praveen Kumar Vemula*, Srujan Marepally* Skin permeable nano-lithocholic-lipidoid efficiently alleviates psoriasis-like chronic skin inflammations. ACS Applied Materials and Interfaces, 2022, 14(13):14859-14870.
  • Abhirup Bagchi, Nivedhitha Devaraju, Karthik Chambayil, Vignesh Rajendiran, Vigneshwaran Venkatesan, Nilofer Sayed, Aswin Anand Pai, Aneesha Nath, Ernest David, Yukio Nakamura, Poonkuzhali Balasubramanian, Alok Srivastava, Saravanabhavan Thangavel, Kumarasamypet M. Mohankumar & Shaji R. Velayudhan. Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications. Scientific Reports volume 12, Article number: 14033 (2022).
  • Das S, Stallon Illangeswaran RS, Ijee S, Kumar S, Velayudhan SR, Balasubramanian P. Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype. J Vis Exp. 2022 Jun 17;(184). doi: 10.3791/63383. PMID: 35786700.
  • Vigneshwaran Venkatesan, Abisha Crystal Christopher, Prathibha Babu, Manoj Kumar K Azhagiri, Kaivalya Walavalkar, Bharath Saravanan, Saranya Srinivasan, Karthik V Karuppusamy, Annlin Jacob, Sumathi Rangaraj, Abhirup Bagchi, Aswin Anand Pai, Yukio Nakamura, Poonkuzhali Balasubramanian, Rekha Pai, Srujan Kumar Marepally, Kumarasamypet Murugesan Mohankumar, Shaji R Velayudhan,  Dimple Notani, Alok Srivastava, Saravanabhavan Thangavel. Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies. DOI:https://doi.org/10.1101/2022.07.11.499646
  • Hubert D-J Daniel, Sanjay Kumar, Rajesh Kannangai, Farzana J, Joseph N Joel, Aby Abraham, Kavitha M Lakshmi, Mavis Agbandje-McKenna, Kirsten E Coleman, Arun Srivastava, Alok Srivastava, Asha M Abraham. Age-stratified adeno-associated virus serotype 3 neutralizing and total antibody prevalence in hemophilia A patient from India. Journal of Medical Virology 2022 May 16. Online ahead of print.  PMID: 35577570 DOI: 10.1002/jmv.27859
  • Devaraju N, Rajendiran V, Ravi NS, Mohankumar KM. Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System. Methods Mol Biol. 2022;2429:307-331. doi: 10.1007/978-1-0716-1979-7_20. PMID: 35507170
  • Precilla S , Kuduvalli S ,  Praveena E , Thangavel S and T S Anitha. Integration of synthetic and natural derivatives revives the therapeutic potential of temozolomide against glioma- an in vitro and in vivo perspective.  Life Sci. 2022 May 6; 301:120609. doi: 10.1016/j.lfs.2022.120609.
  • Mahalingam G, Rachamalla HK, Arjunan P, Periyasami Y, M S, Thangavel S, Mohankumar KM, Moorthy M, Velayudhan SR, Srivastava A, Marepally S. Optimization of SARS-CoV-2 Pseudovirion Production in Lentivirus Backbone With a Novel Liposomal System. Front Pharmacol. 2022 Mar 25;13:840727. doi: 10.3389/fphar.2022.840727. PMID: 35401169; PMCID: PMC8990231.
  • Noel Naveen Johnson, Soosai Manickam Amirtham, B. Sandya Rani, Solomon Sathishkumar, Grace Rebekah, and Elizabeth Vinod. Assessment of the inherent chondrogenic potential of human articular cartilage-derived chondroprogenitors in pellet culture using a novel whole pellet processing approach. Journal of Orthopaedics, March 2022. https://doi.org/10.1016/j.jor.2022.03.007.
  • Karuppusamy K, Demosthenes J, Venkatesan V, Christopher A, Babu P, Azhagiri M, Jacob A, Ramalingam V, Rangaraj S, Mohankumar K.M, Marepally S, Varghese G, Srivastava A, Kannangai R and Thangavel S. The CCR5 gene-edited CD34+CD90+ Hematopoietic stem cell population serves as an optimal graft source for HIV gene therapy. Front. Immunol., 14 March 2022.
  • Ravi NS, Wienert B, Wyman SK, Bell HW, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BP, Devaraju N, Rajendiran V, Syedbasha N, Pai AA, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, DeWitt MA, Crossley M, Corn JE, Mohankumar KM.. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin. Elife. 2022 Feb 11;11:e65421. doi: 10.7554/eLife.65421. PMID: 35147495; PMCID: PMC8865852.
  • Sowmya Ramesh, Farasat Zaman, Lars Sävendahl, Vrisha Madhuri. Radial Shockwave Treatment Promotes Chondrogenesis in Human Growth Plate and Longitudinal Bone Growth in Rabbits. Bone Volume 154, January 2022, 116186.